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Most of the PIONEER trials indicated that oral semaglutide led to a 16 mmHg decrease in systolic blood pressure, and these reductions were statistically significant when comparing the effects of 14 mg oral semaglutide with those of a placebo [6,7,8,9, 12,13,14,15]

It is also approved to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease (Ozempic), and in adults with established cardiovascular disease and either obesity or overweight (Wegovy)

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Lancet: (23), 01291-01296

p = 0.20), with the study by Prately et al